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Suppliers for CAS
1051375-16-6
(4R,12aS)-N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
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Properties | | CAS |
1051375-16-6 | | Formula |
C20H19F2N3O5 |
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19 Registered suppliers
Amadis Chemical Company Limited
P.R.China
More details are to be found here
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
More details are to be found here
H&Z Industry Co.,Ltd
P.R.China
More details are to be found here
Xingrui Industry Co., Limited
P.R.China
More details are to be found here
Capot Chemical Co., Ltd.
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Guangzhou Topwork Chemical Co., Ltd.
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Unilong Industry Co.,Ltd
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
OPQ Chemical Co., Ltd
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
JieJie Group Co., Ltd.
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Shandong Lanhai Industry Co.,Ltd.
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Aea.ltd
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Lori Industry Co., Ltd
P.R.China
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.3787664
Finetech Industry Limited
P.R.China
(4R,12aS)-N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
details
More details are to be found here
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
More details are to be found here
BOC Sciences
USA
Description : Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). - Molecular Weight :419.38
- Boiling Point :669.0±55.0 °C at 760 mmHg
- Purity :≥98%
Molecular Formula : C20H19F2N3O5 Canonical SMILES : CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
InChI :
InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChIKey :
RHWKPHLQXYSBKR-BMIGLBTASA-N
Solubility :
In Vitro: DMSO : 10 mg/mL(23.84 mM;Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one:5% DMSO > > 95% (20%SBE-β-CDin saline) Solubility: ≥ 2.62 mg/mL (6.25 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 3.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 4.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution
Appearance :
White to off-white (Solid)
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
GSK-1349572; GSK 1349572; GSK1349572; Tivicay
More details are to be found here
Shandong SanYoung Industry Co., Ltd
P.R.China
Description : Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). - Molecular Weight :419.38
- Boiling Point :669.0±55.0 °C at 760 mmHg
- Purity :≥98%
Molecular Formula : C20H19F2N3O5 Canonical SMILES : CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
InChI :
InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChIKey :
RHWKPHLQXYSBKR-BMIGLBTASA-N
Solubility :
In Vitro: DMSO : 10 mg/mL(23.84 mM;Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one:5% DMSO > > 95% (20%SBE-β-CDin saline) Solubility: ≥ 2.62 mg/mL (6.25 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 3.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 4.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution
Appearance :
White to off-white (Solid)
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
GSK-1349572; GSK 1349572; GSK1349572; Tivicay
More details are to be found here
AK Scientific, Inc.
USA
Description : Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). - Molecular Weight :419.38
- Boiling Point :669.0±55.0 °C at 760 mmHg
- Purity :≥98%
Molecular Formula : C20H19F2N3O5 Canonical SMILES : CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
InChI :
InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChIKey :
RHWKPHLQXYSBKR-BMIGLBTASA-N
Solubility :
In Vitro: DMSO : 10 mg/mL(23.84 mM;Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one:5% DMSO > > 95% (20%SBE-β-CDin saline) Solubility: ≥ 2.62 mg/mL (6.25 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 3.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 4.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution
Appearance :
White to off-white (Solid)
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
GSK-1349572; GSK 1349572; GSK1349572; Tivicay
More details are to be found here
Santa Cruz Biotechnology, Inc.
USA
Description : Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). - Molecular Weight :419.38
- Boiling Point :669.0±55.0 °C at 760 mmHg
- Purity :≥98%
Molecular Formula : C20H19F2N3O5 Canonical SMILES : CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
InChI :
InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChIKey :
RHWKPHLQXYSBKR-BMIGLBTASA-N
Solubility :
In Vitro: DMSO : 10 mg/mL(23.84 mM;Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one:5% DMSO > > 95% (20%SBE-β-CDin saline) Solubility: ≥ 2.62 mg/mL (6.25 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 3.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution 4.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution
Appearance :
White to off-white (Solid)
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
GSK-1349572; GSK 1349572; GSK1349572; Tivicay
More details are to be found here
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