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BGC > Product Search > Tenofovir alafenamide fumarate | 1392275-56-7
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Suppliers for CAS

1392275-56-7


Properties

CAS   1392275-56-7 
Formula   2[C21H29N6O5P].C4H4O4 

8 Registered suppliers


Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Hangzhou Verychem Science & Technology Co., Ltd. P.R.China
Molecular Formula: 2(C21H29N6O5P).C4H4O4
Shandong Minglang Chemical Co., Ltd P.R.China
Molecular Formula: 2(C21H29N6O5P).C4H4O4
Finetech Industry Limited P.R.China
BOC Sciences USA
Shandong SanYoung Industry Co., Ltd P.R.China
Description :
Tenofovir alafenamide hemifumarate, also known as Tenofovir alafenamide fumarate (2:1), is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevents HIV from multiplying and can reduce the amount of HIV in the body.
  • Molecular Weight :1069.02
  • Purity :> 98%
Molecular Formula :
C46H62N12O14P2
Canonical SMILES :
CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C1N=CN=C2N)OC3=CC=CC=C3.CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C1N=CN=C2N)OC3=CC=CC=C3.C(=CC(=O)O)C(=O)O
InChI :
InChI=1S/2C21H29N6O5P.C4H4O4/c2*1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27;5-3(6)1-2-4(7)8/h2*5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24);1-2H,(H,5,6)(H,7,8)/b;;2-1+/t2*15-,16+,33+;/m11./s1
InChIKey :
SVUJNSGGPUCLQZ-FQQAACOVSA-N
Solubility :
In Vitro: DMSO: 50 mg/mL H2O: 20 mg/mL In Vivo: 1.Add each solvent one by one: 10% DMSO > > 40% PEG300 > > 5% Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (4.68 mM) 2.Add each solvent one by one: 10% DMSO > > 90% (20% SBE-β-CD in saline) Solubility: 2.5 mg/mL (4.68 mM) 3.Add each solvent one by one: 10% DMSO > > 90% corn oil saline Solubility: ≥ 2.5 mg/mL (4.68 mM)
Appearance :
White to Off-White Solid
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
Isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate hemifumarate; TAF; GS734; GS-734; GS 734; GS 7340; GS-7340; GS7340; Tenofovir alafenamide fumarate (2:1)
More details are to be found here
BLD Pharmatech Ltd P.R.China

Detailed information on the suppliers of Tenofovir alafenamide fumarate

Properties:

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