BGC > Product Search > Letermovir | 917389-32-3

Molecular Formula: C29H28F4N4O4
Molecular Weight: 572.5506328

Molecular Formula: C29H28F4N4O4
Molecular Weight: 572.5506328

Molecular Formula: C29H28F4N4O4
Molecular Weight: 572.5506328

EINECS :200-001-8
Molecular formula :C29H28F4N4O4

EINECS :200-001-8
Molecular formula :C29H28F4N4O4

EINECS :200-001-8
Molecular formula :C29H28F4N4O4

EINECS :200-001-8
Molecular formula :C29H28F4N4O4

EINECS :200-001-8
Molecular formula :C29H28F4N4O4

Description :
Letermovir is a novel anti-CMV compound which targets the pUL56 (amino acid 230-370) subunit of the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. It has a novel mode of action targets the enzyme UL56 terminase and keep active to other drug-resistant virus. It has been approved in prophylaxis of CMV infection and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).

• Molecular Weight :572.56
• Boiling Point :706.5±70.0 °C at 760 mmHg
• Purity :≥98%

Molecular Formula :
C29H28F4N4O4
Canonical SMILES :
COC1=C(C=C(C=C1)C(F)(F)F)N2C(C3=C(C(=CC=C3)F)N=C2N4CCN(CC4)C5=CC(=CC=C5)OC)CC(=O)O
InChI :
InChI=1S/C29H28F4N4O4/c1-40-20-6-3-5-19(16-20)35-11-13-36(14-12-35)28-34-27-21(7-4-8-22(27)30)23(17-26(38)39)37(28)24-15-18(29(31,32)33)9-10-25(24)41-2/h3-10,15-16,23H,11-14,17H2,1-2H3,(H,38,39)/t23-/m0/s1
InChIKey :
FWYSMLBETOMXAG-QHCPKHFHSA-N
Solubility :
In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (4.37 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90%(20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (4.37 mM); Clear solution 3.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (4.37 mM); Clear solution
Appearance :
White to Off-white Solid
Application :
Antiviral Agents
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
AIC246; AIC-246; AIC 246; MK-8828; MK 8828; MK8828

More details are to be found here

Purity : 98%
Smile code : FC1=C(N=C(N2CCN(C3=CC=CC(OC)=C3)CC2)N(C4=CC(C(F)(F)F)=CC=C4OC)[C@H]5CC(O)=O)C5=CC=C1
MDL Number : MFCD22572725
MolFormula : C29H28F4N4O4
MolWeight : 572.5506
Available in stock : 3.587

More details are to be found here

Smile code:
FC1=C(N=C(N2CCN(C3=CC=CC(OC)=C3)CC2)N(C4=CC(C(F)(F)F)=CC=C4OC)[C@H]5CC(O)=O)C5=CC=C1
MDL Number:
MFCD22572725
Purity :
98%
Available in stock:
12.931 g

More details are to be found here