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BGC > Product Search > 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)- piperazine monohydrochloride | 98206-09-8
Suppliers for CAS
98206-09-8
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Properties | CAS |
98206-09-8 | Formula |
C12H16N2O2.HCl |
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3 Registered suppliers
Amadis Chemical Company Limited
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C12H16N2O2.ClH Molecular Weight: 256.731
BOC Sciences
USA
Description : Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc.. It is in clinical stage 3. - Molecular Weight :256.73
- Melting Point :256-258 °C
- Purity :> 98 %
Molecular Formula : C12H17N2O2Cl Canonical SMILES : C1CN(CCN1)C2=C3C(=CC=C2)OCCO3.Cl InChI : InChI=1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H InChIKey : JFSOSUNPIXJCIX-UHFFFAOYSA-N Solubility : DMSO: ≥ 31 mg/mL, H2O: ≥ 28 mg/mL Appearance : White to beige powder Application : Eltoprazine hydrochloride has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Storage : -20°C Freezer Synonyms : Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-, monohydrochloride;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride;DU-28853 hydrochloride;DU28853 hydrochloride
More details are to be found here
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Last update 2024-05-13
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