BGC > Product Search > Koumine | 1358-76-5

Molecular Formula: C20H22N2O
Molecular Weight: 306.407

Description :
Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain, and that the reduction in neuropathic pain may be associated with the upregulation of allopregnanolone in the spinal cord. Koumine has the potential to be a future breast cancer chemotherapeutic agent.

• Molecular Weight :306.4
• Boiling Point :436.5±45.0°C (Predicted)
• Melting Point :168℃
• Purity :> 98%

Molecular Formula :
C20H22N2O
Canonical SMILES :
CN1CC2(C3CC4C5=NC6=CC=CC=C6C52CC1C3CO4)C=C
InChI :
InChI=1S/C20H22N2O/c1-3-19-11-22(2)16-9-20(19)13-6-4-5-7-15(13)21-18(20)17-8-14(19)12(16)10-23-17/h3-7,12,14,16-17H,1,8-11H2,2H3/t12-,14+,16-,17+,19-,20+/m0/s1
InChIKey :
VTLYEMHGPMGUOT-FXWNUWCSSA-N
Appearance :
Powder
Application :
Antineoplastic
Storage : 2-8°C
Synonyms :
(3R,7alpha,20alpha)-1,2,18,19-Tetradehydro-3,17-epoxy-7,20(2H,19H)cyclovobasan; 7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-, (3R,7alpha,20alpha)-

More details are to be found here

Description :
Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain, and that the reduction in neuropathic pain may be associated with the upregulation of allopregnanolone in the spinal cord. Koumine has the potential to be a future breast cancer chemotherapeutic agent.

• Molecular Weight :306.4
• Boiling Point :436.5±45.0°C (Predicted)
• Melting Point :168℃
• Purity :> 98%

Molecular Formula :
C20H22N2O
Canonical SMILES :
CN1CC2(C3CC4C5=NC6=CC=CC=C6C52CC1C3CO4)C=C
InChI :
InChI=1S/C20H22N2O/c1-3-19-11-22(2)16-9-20(19)13-6-4-5-7-15(13)21-18(20)17-8-14(19)12(16)10-23-17/h3-7,12,14,16-17H,1,8-11H2,2H3/t12-,14+,16-,17+,19-,20+/m0/s1
InChIKey :
VTLYEMHGPMGUOT-FXWNUWCSSA-N
Appearance :
Powder
Application :
Antineoplastic
Storage : 2-8°C
Synonyms :
(3R,7alpha,20alpha)-1,2,18,19-Tetradehydro-3,17-epoxy-7,20(2H,19H)cyclovobasan; 7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-, (3R,7alpha,20alpha)-

More details are to be found here