BGC > Product Search > (2R,3S,5R)-5-(6-Amino-2-fluoropurin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol | 865363-93-5
Suppliers for CAS
865363-93-5
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Properties | CAS |
865363-93-5 |
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7 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C12H12FN5O3 Molecular Weight: 293.2537832
JieJie Group Co., Ltd.
P.R.China
Molecular Formula: C12H12FN5O3 Molecular Weight: 293.2537832
Finetech Industry Limited
P.R.China
More details are to be found here
NewCan Biotech Limited
P.R.China
More details are to be found here
More details are to be found here
BOC Sciences
USA
Description : Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. - Molecular Weight :293.25
- Boiling Point :669.2±65.0 °C(Predicted)
- Melting Point :220.0-221.4 °C (dec.)
- Purity :99.94%
Molecular Formula : C12H12FN5O3 Canonical SMILES : C#CC1(C(CC(O1)N2C=NC3=C(N=C(N=C32)F)N)O)CO InChI : InChI=1S/C12H12FN5O3/c1-2-12(4-19)6(20)3-7(21-12)18-5-15-8-9(14)16-11(13)17-10(8)18/h1,5-7,19-20H,3-4H2,(H2,14,16,17)/t6-,7+,12+/m0/s1 InChIKey : IKKXOSBHLYMWAE-QRPMWFLTSA-N Solubility : In Vitro: DMSO : 100 mg/mL(341.01 mM;Need ultrasonic) H2O : 3.57 mg/mL(12.17 mM;ultrasonic and warming and heat to 60°C) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.08 mg/mL (7.09 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90% (20%SBE-β-CD in saline) Solubility: ≥ 2.08 mg/mL (7.09 mM); Clear solution 3.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.08 mg/mL (7.09 mM); Clear solution 4.Add each solvent one by one:PBS Solubility: 1.35 mg/mL (4.60 mM); Clear solution; Need ultrasonic 5.Add each solvent one by one:5% DMSO > > 40%PEG300 > > 5%Tween-80 > > 50% saline Solubility: ≥ 1.1 mg/mL (3.75 mM); Clear solution 6.Add each solvent one by one:5% DMSO > > 95% (20%SBE-β-CD in saline) Solubility: ≥ 1.1 mg/mL (3.75 mM); Clear solution Appearance : White to off-white (Solid) Application : Enzyme Inhibitors Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month Synonyms : EFdA; 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine
More details are to be found here
Allfluoro Pharmaceutical Co. Ltd.
P.R.China
MF: C12H12FN5O3 MW: 293,25
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