BGC > Product Search > 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone | 571203-78-6
Suppliers for CAS
571203-78-6
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Properties | CAS |
571203-78-6 | Formula |
C30H31ClN4O4 |
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7 Registered suppliers
Amadis Chemical Company Limited
P.R.China
More details are to be found here
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C30H31ClN4O4 Molecular Weight: 547.06 Hazard Symbols: T UN Number: UN 2811 6.1/PG 3 WGKGermany: 3
Aea.ltd
P.R.China
Molecular Formula: C30H31ClN4O4 Molecular Weight: 547.06 Hazard Symbols: T UN Number: UN 2811 6.1/PG 3 WGKGermany: 3
BOC Sciences
USA
Description : Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. - Molecular Weight :547.04454
- Purity :0.98
Molecular Formula : C30H31ClN4O4 Canonical SMILES : CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl InChI : InChI=1S/C30H31ClN4O4/c1-3-38-27-11-7-6-10-26(27)35-29(32-25-9-5-4-8-24(25)30(35)37)21(2)33-16-18-34(19-17-33)28(36)20-39-23-14-12-22(31)13-15-23/h4-15,21H,3,16-20H2,1-2H3 InChIKey : BKQFRNYHFIQEKN-UHFFFAOYSA-N Appearance : white solid powder Synonyms : Erastin
More details are to be found here
Chemos GmbH & Co. KG
Germany
Description : Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. - Molecular Weight :547.04454
- Purity :0.98
Molecular Formula : C30H31ClN4O4 Canonical SMILES : CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl InChI : InChI=1S/C30H31ClN4O4/c1-3-38-27-11-7-6-10-26(27)35-29(32-25-9-5-4-8-24(25)30(35)37)21(2)33-16-18-34(19-17-33)28(36)20-39-23-14-12-22(31)13-15-23/h4-15,21H,3,16-20H2,1-2H3 InChIKey : BKQFRNYHFIQEKN-UHFFFAOYSA-N Appearance : white solid powder Synonyms : Erastin
More details are to be found here
Santa Cruz Biotechnology, Inc.
USA
Description : Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. - Molecular Weight :547.04454
- Purity :0.98
Molecular Formula : C30H31ClN4O4 Canonical SMILES : CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl InChI : InChI=1S/C30H31ClN4O4/c1-3-38-27-11-7-6-10-26(27)35-29(32-25-9-5-4-8-24(25)30(35)37)21(2)33-16-18-34(19-17-33)28(36)20-39-23-14-12-22(31)13-15-23/h4-15,21H,3,16-20H2,1-2H3 InChIKey : BKQFRNYHFIQEKN-UHFFFAOYSA-N Appearance : white solid powder Synonyms : Erastin
More details are to be found here
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