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BGC > Product Search > Tafamidis | 594839-88-0
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Suppliers for CAS

594839-88-0



 

Properties

CAS   594839-88-0 
Formula   C14H7Cl2NO3 

8 Registered suppliers


Amadis Chemical Company Limited P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C14H7Cl2NO3
Molecular Weight: 308.12
Finetech Industry Limited P.R.China
BOC Sciences USA
AK Scientific, Inc. USA
Description :
Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. It is a drug for the amelioration of transthyretin-related hereditary amyloidosis. It functions by kinetic stabilization of the correctly folded tetrameric form of the transthyretin (TTR) protein and binds selectively and with negative cooperativity to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR.
  • Molecular Weight :308.12
  • Purity :> 98%
Molecular Formula :
C14H7Cl2NO3
Canonical SMILES :
C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
InChI :
InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
InChIKey :
TXEIIPDJKFWEEC-UHFFFAOYSA-N
Synonyms :
Fx-1006A; Vyndaqel
More details are to be found here
Chemos GmbH & Co. KG Germany
Description :
Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. It is a drug for the amelioration of transthyretin-related hereditary amyloidosis. It functions by kinetic stabilization of the correctly folded tetrameric form of the transthyretin (TTR) protein and binds selectively and with negative cooperativity to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR.
  • Molecular Weight :308.12
  • Purity :> 98%
Molecular Formula :
C14H7Cl2NO3
Canonical SMILES :
C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
InChI :
InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
InChIKey :
TXEIIPDJKFWEEC-UHFFFAOYSA-N
Synonyms :
Fx-1006A; Vyndaqel
More details are to be found here
Chemtour Biotech Co., Ltd P.R.China
Description :
Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. It is a drug for the amelioration of transthyretin-related hereditary amyloidosis. It functions by kinetic stabilization of the correctly folded tetrameric form of the transthyretin (TTR) protein and binds selectively and with negative cooperativity to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR.
  • Molecular Weight :308.12
  • Purity :> 98%
Molecular Formula :
C14H7Cl2NO3
Canonical SMILES :
C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
InChI :
InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
InChIKey :
TXEIIPDJKFWEEC-UHFFFAOYSA-N
Synonyms :
Fx-1006A; Vyndaqel
More details are to be found here

Detailed information on the suppliers of Tafamidis

Properties:

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