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BGC > Product Search > Tariquidar | 206873-63-4
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Suppliers for

Tariquidar



Properties

CAS   206873-63-4 
Formula   C38H38N4O6 

Structure

6 Registered suppliers


Molecular Formula: C38H38N4O6
Molecular Weight: 646.73

More details are to be found here
Description :
Tariquidar, also known as XR9576, is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity.
  • Molecular Weight :646.744
  • Purity :> 98%
Molecular Formula :
C38H38N4O6
Canonical SMILES :
COC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=CC=C6N=C5)OC)OC)OC
InChI :
InChI=1S/C38H38N4O6/c1-45-33-18-25-14-16-42(23-28(25)19-34(33)46-2)15-13-24-9-11-29(12-10-24)40-38(44)30-20-35(47-3)36(48-4)21-32(30)41-37(43)27-17-26-7-5-6-8-31(26)39-22-27/h5-12,17-22H,13-16,23H2,1-4H3,(H,40,44)(H,41,43)
InChIKey :
LGGHDPFKSSRQNS-UHFFFAOYSA-N
Appearance :
light yellow solid powder
Synonyms :
XR 9576; XR9576; XR-9576; D06008

More details are to be found here
Description :
Tariquidar, also known as XR9576, is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity.
  • Molecular Weight :646.744
  • Purity :> 98%
Molecular Formula :
C38H38N4O6
Canonical SMILES :
COC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=CC=C6N=C5)OC)OC)OC
InChI :
InChI=1S/C38H38N4O6/c1-45-33-18-25-14-16-42(23-28(25)19-34(33)46-2)15-13-24-9-11-29(12-10-24)40-38(44)30-20-35(47-3)36(48-4)21-32(30)41-37(43)27-17-26-7-5-6-8-31(26)39-22-27/h5-12,17-22H,13-16,23H2,1-4H3,(H,40,44)(H,41,43)
InChIKey :
LGGHDPFKSSRQNS-UHFFFAOYSA-N
Appearance :
light yellow solid powder
Synonyms :
XR 9576; XR9576; XR-9576; D06008

More details are to be found here

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Properties:

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