BGC > Product Search > PKC-412 | 120685-11-2

Molecular Formula: C35H30N4O4
Molecular Weight: 570.646
Hazard Symbols: T
HS Code: 29329990

Molecular Formula: C35H30N4O4
Molecular Weight: 570.646
Hazard Symbols: T
HS Code: 29329990

Description :
Midostaurin is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus.

• Molecular Weight :570.65
• Melting Point :225-235 °C
• Purity :≥98%

Molecular Formula :
C35H30N4O4
Canonical SMILES :
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
InChI :
InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1
InChIKey :
BMGQWWVMWDBQGC-IIFHNQTCSA-N
Solubility :
Soluble in DMSO, Dichloromethane, Water
Appearance :
Light Yellow to Yellow Solid
Storage : Store at -20°C
Synonyms :
PKC412; PKC-412; PKC 412; PKC412A; PKC-412A; PKC 412A; CGP41251; CGP 41251; CGP-41251; Benzoylstaurosporine; 4'-N-Benzoylstaurosporine

More details are to be found here

Smile code:
O=C(N([C@H]1[C@@H](OC)[C@@](O2)(C)N3C4=CC=CC=C4C5=C3C6=C(C7=CC=CC=C7N6[C@@]2([H])C1)C8=C5CNC8=O)C)C9=CC=CC=C9
MDL Number:
MFCD00871372
Purity :
99%
Available in stock:
27.144 g

More details are to be found here

Smile code:
O=C(N([C@H]1[C@@H](OC)[C@@](O2)(C)N3C4=CC=CC=C4C5=C3C6=C(C7=CC=CC=C7N6[C@@]2([H])C1)C8=C5CNC8=O)C)C9=CC=CC=C9
MDL Number:
MFCD00871372
Purity :
99%
Available in stock:
27.144 g

More details are to be found here

Smile code:
O=C(N([C@H]1[C@@H](OC)[C@@](O2)(C)N3C4=CC=CC=C4C5=C3C6=C(C7=CC=CC=C7N6[C@@]2([H])C1)C8=C5CNC8=O)C)C9=CC=CC=C9
MDL Number:
MFCD00871372
Purity :
99%
Available in stock:
27.144 g

More details are to be found here