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Suppliers for
ONO-4059 (hydrochloride)
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Properties | CAS |
1439901-97-9 |
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2 Registered suppliers
Description : ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Molecular Formula : C25H23ClN6O3 Canonical SMILES : O=C(N1C[C@@H](CC1)N(C2=O)C3=NC=NC(N)=C3N2C4=CC=C(C=C4)OC5=CC=CC=C5)C#CC.[H]Cl InChI : 1S/C25H22N6O3.ClH/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19;/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28);1H/t18-;/m1./s1 InChIKey : UQYDCIJFACDXSG-GMUIIQOCSA-N Solubility : Soluble in DMSO Appearance : Solid powder Storage : Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -55℃ for long term (months to years). Synonyms : (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride; ONO-4059 HCl; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib
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Last update 2024-05-31
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