Suppliers for CAS
1001264-89-6
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Properties | CAS |
1001264-89-6 | Formula |
C24H32ClN5O2 |
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4 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C24H32ClN5O2 Molecular Weight: 457.99618
Aea.ltd
P.R.China
Molecular Formula: C24H32ClN5O2 Molecular Weight: 457.99618
Molecular Formula: C24H32ClN5O2 Molecular Weight: 457.99618
BOC Sciences
USA
Description : Ipatasertib, also known as GDC-0068 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Molecular Formula : C24H32ClN5O2 Canonical SMILES : CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O InChI : InChI=1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3H3/t16-,19-,20-/m1/s1 InChIKey : GRZXWCHAXNAUHY-NSISKUIASA-N Appearance : Solid powder Application : Antineoplastic Agents Synonyms : GDC-0068; GDC0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib
More details are to be found here
Chemos GmbH & Co. KG
Germany
Description : Ipatasertib, also known as GDC-0068 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Molecular Formula : C24H32ClN5O2 Canonical SMILES : CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O InChI : InChI=1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3H3/t16-,19-,20-/m1/s1 InChIKey : GRZXWCHAXNAUHY-NSISKUIASA-N Appearance : Solid powder Application : Antineoplastic Agents Synonyms : GDC-0068; GDC0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib
More details are to be found here
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