BGC > Product Search > Ambrisentan

Molecular Formula: C22H22N2O4
Molecular Weight: 378.42
HS Code: 29335990

Molecular Formula: C22H22N2O4
Molecular Weight: 378.42
HS Code: 29335990

Description :
Ambrisentan, a highly selective antagonist of the endothelin-1 type A receptor with IC50 of 18 nM, is indicated for the treatment of pulmonary arterial hypertension (PAH).

• Molecular Weight :378.42
• Melting Point :> 150 °C
• Purity :> 98%

Molecular Formula :
C22H22N2O4
Canonical SMILES :
CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C
InChI :
InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1
InChIKey :
OUJTZYPIHDYQMC-LJQANCHMSA-N
Solubility :
Ambrisentan is practically insoluble in aqueous solutions at low pH. Solubility increases at higher pH.
Appearance :
White to off white solid
Application :
Antihypertensive Agents
Synonyms :
BSF-208075; BSF208075; BSF 208075; LU-208075; LU208075; LU 208075; Letairis; Volibris

More details are to be found here

Purity : 98%
Smile code : O=C(O)[C@@H](OC1=NC(C)=CC(C)=N1)C(C2=CC=CC=C2)(OC)C3=CC=CC=C3
MDL Number : MFCD08672619
MolFormula : C22H22N2O4
MolWeight : 378.4211
Available in stock : 47.412

More details are to be found here

Purity : 98%
Smile code : O=C(O)[C@@H](OC1=NC(C)=CC(C)=N1)C(C2=CC=CC=C2)(OC)C3=CC=CC=C3
MDL Number : MFCD08672619
MolFormula : C22H22N2O4
MolWeight : 378.4211
Available in stock : 47.412

More details are to be found here

Purity : 98%
Smile code : O=C(O)[C@@H](OC1=NC(C)=CC(C)=N1)C(C2=CC=CC=C2)(OC)C3=CC=CC=C3
MDL Number : MFCD08672619
MolFormula : C22H22N2O4
MolWeight : 378.4211
Available in stock : 47.412

More details are to be found here

Purity : 98%
Smile code : O=C(O)[C@@H](OC1=NC(C)=CC(C)=N1)C(C2=CC=CC=C2)(OC)C3=CC=CC=C3
MDL Number : MFCD08672619
MolFormula : C22H22N2O4
MolWeight : 378.4211
Available in stock : 47.412

More details are to be found here

Purity : 98%
Smile code : O=C(O)[C@@H](OC1=NC(C)=CC(C)=N1)C(C2=CC=CC=C2)(OC)C3=CC=CC=C3
MDL Number : MFCD08672619
MolFormula : C22H22N2O4
MolWeight : 378.4211
Available in stock : 47.412

More details are to be found here