BGC > Product Search > Apalutamide

EINECS :807-449-9
Molecular formula :C21H15F4N5O2S

EINECS :807-449-9
Molecular formula :C21H15F4N5O2S

EINECS :807-449-9
Molecular formula :C21H15F4N5O2S

EINECS :807-449-9
Molecular formula :C21H15F4N5O2S

Description :
Apalutamide is a potent and competitive androgen receptor (AR) antagonist with potential antineoplastic activity. It binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus.

• Molecular Weight :477.43
• Purity :98%

Molecular Formula :
C21H15F4N5O2S
Canonical SMILES :
CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CN=C(C(=C4)C(F)(F)F)C#N)F
InChI :
InChI=1S/C21H15F4N5O2S/c1-27-17(31)13-4-3-11(8-15(13)22)30-19(33)29(18(32)20(30)5-2-6-20)12-7-14(21(23,24)25)16(9-26)28-10-12/h3-4,7-8,10H,2,5-6H2,1H3,(H,27,31)
InChIKey :
HJBWBFZLDZWPHF-UHFFFAOYSA-N
Appearance :
White to Off-white Solid Powder
Synonyms :
ARN-509; Apalutamide; ARN 509; JNJ56021927; JNJ-56021927; JNJ 56021927; ARN509; 4-[7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide

More details are to be found here

Purity : 98%
Smile code : O=C(NC)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43CCC4)C=C1F
MDL Number : MFCD22380626
MolFormula : C21H15F4N5O2S
MolWeight : 477.4347
Available in stock : 202.125

More details are to be found here