BGC > Product Search > Raltegravir potassium salt

Molecular Formula: C20H20FN6O5.K
Molecular Weight: 482.511
HS Code: 2934990002

Molecular Formula: C20H20FN6O5.K
Molecular Weight: 482.511
HS Code: 2934990002

Molecular Formula: C20H20FN6O5.K
Molecular Weight: 482.511
HS Code: 2934990002

Molecular Formula: C20H20FN6O5.K
Molecular Weight: 482.511
HS Code: 2934990002

Description :
Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents.

• Molecular Weight :482.514
• Melting Point :155-157˚C (dec.)
• Purity :98%

Molecular Formula :
C20H20FKN6O5
Canonical SMILES :
CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)[O-])C(=O)NCC3=CC=C(C=C3)F.[K+]
InChI :
InChI=1S/C20H21FN6O5.K/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11;/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30);/q;+1/p-1
InChIKey :
IFUKBHBISRAZTF-UHFFFAOYSA-M
Solubility :
In Vitro: H2O: 25 mg/mL (51.81 mM; Need ultrasonic) DMSO : 6 mg/mL (12.43 mM; Need ultrasonic) In Vivo: 1.Add each solvent one by one: 10% DMSO > > 90% corn oil Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution 2.Add each solvent one by one: 10% DMSO > > 40% PEG300 > > 5% Tween-80 > > 45% saline Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution 3.Add each solvent one by one: 10% DMSO > > 90% (20% SBE-β-CD in saline) Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution
Appearance :
White crystalline powder
Application :
Anti-HIV Agents
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
MK-0518; MK 0518; MK0518; Raltegravir

More details are to be found here

Description :
Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents.

• Molecular Weight :482.514
• Melting Point :155-157˚C (dec.)
• Purity :98%

Molecular Formula :
C20H20FKN6O5
Canonical SMILES :
CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)[O-])C(=O)NCC3=CC=C(C=C3)F.[K+]
InChI :
InChI=1S/C20H21FN6O5.K/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11;/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30);/q;+1/p-1
InChIKey :
IFUKBHBISRAZTF-UHFFFAOYSA-M
Solubility :
In Vitro: H2O: 25 mg/mL (51.81 mM; Need ultrasonic) DMSO : 6 mg/mL (12.43 mM; Need ultrasonic) In Vivo: 1.Add each solvent one by one: 10% DMSO > > 90% corn oil Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution 2.Add each solvent one by one: 10% DMSO > > 40% PEG300 > > 5% Tween-80 > > 45% saline Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution 3.Add each solvent one by one: 10% DMSO > > 90% (20% SBE-β-CD in saline) Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution
Appearance :
White crystalline powder
Application :
Anti-HIV Agents
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
MK-0518; MK 0518; MK0518; Raltegravir

More details are to be found here

Description :
Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents.

• Molecular Weight :482.514
• Melting Point :155-157˚C (dec.)
• Purity :98%

Molecular Formula :
C20H20FKN6O5
Canonical SMILES :
CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)[O-])C(=O)NCC3=CC=C(C=C3)F.[K+]
InChI :
InChI=1S/C20H21FN6O5.K/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11;/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30);/q;+1/p-1
InChIKey :
IFUKBHBISRAZTF-UHFFFAOYSA-M
Solubility :
In Vitro: H2O: 25 mg/mL (51.81 mM; Need ultrasonic) DMSO : 6 mg/mL (12.43 mM; Need ultrasonic) In Vivo: 1.Add each solvent one by one: 10% DMSO > > 90% corn oil Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution 2.Add each solvent one by one: 10% DMSO > > 40% PEG300 > > 5% Tween-80 > > 45% saline Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution 3.Add each solvent one by one: 10% DMSO > > 90% (20% SBE-β-CD in saline) Solubility: ≥ 0.6 mg/mL (1.24 mM); Clear solution
Appearance :
White crystalline powder
Application :
Anti-HIV Agents
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
MK-0518; MK 0518; MK0518; Raltegravir

More details are to be found here