BGC > Product Search > Celastrol

Molecular Formula: C29H38O4
Molecular Weight: 450.61
Hazard Symbols: T
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 2
HS Code: 29189900

Molecular Formula: C29H38O4
Molecular Weight: 450.61
Hazard Symbols: T
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 2
HS Code: 29189900

Molecular Formula: C29H38O4
Molecular Weight: 450.61
Hazard Symbols: T
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 2
HS Code: 29189900

Molecular Formula: C29H38O4
Molecular Weight: 450.61
Hazard Symbols: T
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 2
HS Code: 29189900

Molecular Formula : C29H38O4
Molecular Weight : 450.61
Appearance : Red crystalline powder
Assay : ≥98%

Molecular Formula : C29H38O4
Molecular Weight : 450.61
Appearance : Red crystalline powder
Assay : ≥98%

Description :
Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.

• Molecular Weight :450.61
• Boiling Point :645.7±55.0°C (Predicted)
• Melting Point :190-220°C
• Purity :> 98%

Molecular Formula :
C29H38O4
Canonical SMILES :
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
InChI :
InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChIKey :
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Solubility :
Soluble in Chloroform (Slightly), Hexanes (Slightly, Heated), Methanol
Appearance :
Red powder
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
Tripterin; Tripterine; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; NSC70931; 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid,3-hydroxy-9,13-dimethyl-2-oxo-, (9b,13a,14b,20a)-; 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

More details are to be found here

Description :
Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.

• Molecular Weight :450.61
• Boiling Point :645.7±55.0°C (Predicted)
• Melting Point :190-220°C
• Purity :> 98%

Molecular Formula :
C29H38O4
Canonical SMILES :
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
InChI :
InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChIKey :
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Solubility :
Soluble in Chloroform (Slightly), Hexanes (Slightly, Heated), Methanol
Appearance :
Red powder
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
Tripterin; Tripterine; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; NSC70931; 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid,3-hydroxy-9,13-dimethyl-2-oxo-, (9b,13a,14b,20a)-; 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

More details are to be found here

Description :
Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.

• Molecular Weight :450.61
• Boiling Point :645.7±55.0°C (Predicted)
• Melting Point :190-220°C
• Purity :> 98%

Molecular Formula :
C29H38O4
Canonical SMILES :
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
InChI :
InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChIKey :
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Solubility :
Soluble in Chloroform (Slightly), Hexanes (Slightly, Heated), Methanol
Appearance :
Red powder
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
Tripterin; Tripterine; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; NSC70931; 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid,3-hydroxy-9,13-dimethyl-2-oxo-, (9b,13a,14b,20a)-; 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

More details are to be found here

Description :
Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.

• Molecular Weight :450.61
• Boiling Point :645.7±55.0°C (Predicted)
• Melting Point :190-220°C
• Purity :> 98%

Molecular Formula :
C29H38O4
Canonical SMILES :
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
InChI :
InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChIKey :
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Solubility :
Soluble in Chloroform (Slightly), Hexanes (Slightly, Heated), Methanol
Appearance :
Red powder
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
Tripterin; Tripterine; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; NSC70931; 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid,3-hydroxy-9,13-dimethyl-2-oxo-, (9b,13a,14b,20a)-; 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

More details are to be found here

Description :
Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.

• Molecular Weight :450.61
• Boiling Point :645.7±55.0°C (Predicted)
• Melting Point :190-220°C
• Purity :> 98%

Molecular Formula :
C29H38O4
Canonical SMILES :
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
InChI :
InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChIKey :
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Solubility :
Soluble in Chloroform (Slightly), Hexanes (Slightly, Heated), Methanol
Appearance :
Red powder
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
Tripterin; Tripterine; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; NSC70931; 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid,3-hydroxy-9,13-dimethyl-2-oxo-, (9b,13a,14b,20a)-; 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

More details are to be found here

Description :
Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.

• Molecular Weight :450.61
• Boiling Point :645.7±55.0°C (Predicted)
• Melting Point :190-220°C
• Purity :> 98%

Molecular Formula :
C29H38O4
Canonical SMILES :
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
InChI :
InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChIKey :
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Solubility :
Soluble in Chloroform (Slightly), Hexanes (Slightly, Heated), Methanol
Appearance :
Red powder
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
Tripterin; Tripterine; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; NSC70931; 24,25,26-Trinoroleana-1(10),3,5,7-tetraen-29-oic acid,3-hydroxy-9,13-dimethyl-2-oxo-, (9b,13a,14b,20a)-; 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid

More details are to be found here