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Suppliers for
Dxd
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Properties | CAS |
1599440-33-1 |
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4 Registered suppliers
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Description : DXD, an Exatecan derivative for ADC, is a potent DNA topoisomerase I inhibitor with an IC50 of 0.31 μM. It can be used as a payload for antibody-conjugated drug ADCs targeting HER2. - Molecular Weight :493.48
- Boiling Point :957.9±65.0°C (Predicted)
- Purity :≥95%
Molecular Formula : C26H24FN3O6 Canonical SMILES : CCC1(C2=C(COC1=O)C(=O)N3CC4=C5C(CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)CO)O InChI : InChI=1S/C26H24FN3O6/c1-3-26(35)15-6-19-23-13(8-30(19)24(33)14(15)10-36-25(26)34)22-17(28-20(32)9-31)5-4-12-11(2)16(27)7-18(29-23)21(12)22/h6-7,17,31,35H,3-5,8-10H2,1-2H3,(H,28,32)/t17-,26-/m0/s1 InChIKey : PLXLYXLUCNZSAA-QLXKLKPCSA-N Solubility : Soluble in DMSO Appearance : Solid Powder Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years) Synonyms : N-((1S,9S)-9-Ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinolin-1-yl)-2-hydroxyacetamide
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Dxd
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Properties:
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Last update 2024-05-28
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