Description:
OTSSP167 is a potent inhibitor of Maternal embryonic leucine zipper kinase (MELK) which regulates neural stem cell selfrenewal through control of the cell cycle.
Molecular Formula:
C25H29Cl3N4O2
Canonical SMILES:
CC(=O)C1=CN=C2C=CC(=NC2=C1NC3CCC(CC3)CN(C)C)C4=CC(=C(C(=C4)Cl)O)Cl.Cl
InChI:
InChI=1S/C25H28Cl2N4O2.ClH/c1-14(32)18-12-28-22-9-8-21(16-10-19(26)25(33)20(27)11-16)30-24(22)23(18)29-17-6-4-15(5-7-17)13-31(2)3;/h8-12,15,17,33H,4-7,13H2,1-3H3,(H,28,29);1H
InChIKey:
XDGWHISAOWEFML-UHFFFAOYSA-N
Solubility:
Soluble in DMSO.
Appearance:
Light Yellow Solid Powder
Storage: Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -45℃ for long term (months to years).
Synonyms:
4-[7-acetyl-8-[[4-[(dimethylamino)methyl]cyclohexyl]amino]-1H-1,5-naphthyridin-2-ylidene]-2,6-dichlorocyclohexa-2,5-dien-1-one hydrochloride; OTSSP167 (hydrochloride); UNII-65P731R507; 65P731R507; OTSSP167 HCl; OTS-167 monohydrochloride; HY-15512A; AKOS025117447 Más detalles se encuentran
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