BGC > Buscar Producto > Motesanib diphosphate | 857876-30-3

Molecular Formula: C22H29N5O9P2
Molecular Weight: 569.441282

Description:
Motesanib Diphosphate is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.

• Molecular Weight:569.44
• Purity:>98%

Molecular Formula:
C22H29N5O9P2
Canonical SMILES:
CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C.OP(=O)(O)O.OP(=O)(O)O
InChI:
InChI=1S/C22H23N5O.2H3O4P/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15;2*1-5(2,3)4/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28);2*(H3,1,2,3,4)
InChIKey:
ONDPWWDPQDCQNJ-UHFFFAOYSA-N
Application:
Protein Kinase Inhibitors
Synonyms:
Motesanib diphosphate; 857876-30-3; AMG-706; Motesanib (Diphosphate); Motesanib Diphosphate (AMG-706); Motesanib diphosphate [USAN]; Motesanib phosphate; AMG 706 (Diphosphate); AMG 706; ; T6Q3060U91; Motesanib phosphate (JAN); Motesanib diphosphate (USAN); N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide; phosphoric acid; MOTESANIB PHOSPHATE [JAN]; 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-((4-pyridinylmethyl)amino)-, phosphate (1:2)