BGC > Buscar Producto > Betulinic acid | 472-15-1

Molecular Formula: C30H48O3

Appearance	White powder
Odor	Characteristic
Assay (HPLC)	Betulinic Acid ≥ 98%
Sieve analysis	NLT 95% pass 80 mesh
Loss on Drying	≤ 5.0%
Ash	≤ 5.0%
Heavy Metal
Pb	<2ppm
As	<2ppm
Hg	<2ppm
Residual Solvent	Eur.Pharm
Microbiology
Total Plate Count	<1000cfu/g
Yeast & Moulds	<100cfu/g
E.Coli	Negative
Salmonella	Negative
Salmonella	Negative

Molecular Formula: C30H48O3
Molecular Weight: 456.7
Hazard Symbols: Xi
WGKGermany: 3
HS Code: 29181985

EINECS:207-448-8
Molecular formula:C30H48O3

Description:
Betulinic acid is a pentacyclic lupane-type triterpene derivative of betulin with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation. Betulinic acid is a natural compound found in the herbs of Ziziphus jujuba. It can be used in cosmetics material.

• Molecular Weight:456.7
• Boiling Point:550.0±33.0 °C at 760 mmHg
• Melting Point:295-298 °C (dec.)(lit.)
• Purity:0.98

Molecular Formula:
C30H48O3
Canonical SMILES:
CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C(=O)O
InChI:
InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChIKey:
QGJZLNKBHJESQX-FZFNOLFKSA-N
Solubility:
In Vitro: DMSO : 35.71 mg/mL(78.19 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: 2.5 mg/mL (5.47 mM); Suspended solution; Need ultrasonic 2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: 2.5 mg/mL (5.47 mM); Suspended solution; Need ultrasonic 3.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.08 mg/mL (4.55 mM); Clear solution
Appearance:
White to off-white Solid
Application:
Anti-melanogenic/antitumor/anti-HIV
Storage: 4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light)
Synonyms:
ALS357; ALS 357; ALS-357; Mairin; Acronym: BA; Code name: ALS-357.