BGC > Buscar Producto > 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide | 109889-09-0

Molecular Formula: C18H24N4O
Molecular Weight: 312,41

Description:
Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medull

• Molecular Weight:312.42
• Melting Point:290-292°C
• Purity:> 95%

Molecular Formula:
C18H24N4O
Canonical SMILES:
MFWNKCLOYSRHCJ-AGUYFDCRSA-N
InChI:
InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)/t12?,13-,14+
InChIKey:
MFWNKCLOYSRHCJ-AGUYFDCRSA-N
Solubility:
25°C: DMSO
Appearance:
White to yellowish white crystalline powder
Application:
Granisetron is an antagonist of serptpmom 5-HT3 receptor and could be used to relieve the nausea and vomiting symptom after receving chemotherapy by decreasing the activity of the vagus nerve.
Storage: -20ºC Freeze
Synonyms:
1-methyl-n-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-indazole-3-carboxamide; 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, endo-; BRL 43694