BGC > Produktsuche > WAY-316606 | 915759-45-4

Molecular Formula: C18H19F3N2O4S2
Molecular Weight: 448.4796696

Description:
WAY-316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. Modulators of the Wnt pathway have been proposed as anabolic agents for the treatment of osteoporosis or other bone-related disorders. WAY-316606 bound to sFRP-1 with a Kd of 0.08 mM and inhibited it with an EC50 of 0.65 mM.

• Molecular Weight:448.475
• Purity:>98%

Molecular Formula:
C18H19F3N2O4S2
Canonical SMILES:
C1CNCCC1NS(=O)(=O)C2=C(C=CC(=C2)S(=O)(=O)C3=CC=CC=C3)C(F)(F)F
InChI:
InChI=1S/C18H19F3N2O4S2/c19-18(20,21)16-7-6-15(28(24,25)14-4-2-1-3-5-14)12-17(16)29(26,27)23-13-8-10-22-11-9-13/h1-7,12-13,22-23H,8-11H2
InChIKey:
ITBGJNVZJBVPLJ-UHFFFAOYSA-N
Appearance:
White Solid
Synonyms:
WAY 316606; 5-(phenylsulfonyl)-N-(piperidin-4-yl)-2-(trifluoromethyl)benzenesulfonamide