BGC > Produktsuche > Pfk15 | 4382-63-2

Molecular Formula: C17H12N2O
Molecular Weight: 260.28998
Hazard Symbols: Xi
WGKGermany: 3

Description:
PFK15 is a potent and selective inhibitor of 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. Overexpression of the PFKFB3 enzyme leads to high glycolytic metabolism, which is required for cancer cells to survive in the harsh tumor microenvironment.

• Molecular Weight:260.29
• Boiling Point:464.4±45.0 °C at 760 mmHg
• Purity:>98%

Molecular Formula:
C17H12N2O
Canonical SMILES:
C1=CC=C2C(=C1)C=CC(=N2)C=CC(=O)C3=CC=NC=C3
InChI:
InChI=1S/C17H12N2O/c20-17(14-9-11-18-12-10-14)8-7-15-6-5-13-3-1-2-4-16(13)19-15/h1-12H/b8-7+
InChIKey:
UJJUKZPBUMCSJZ-BQYQJAHWSA-N
Synonyms:
PFK 015; PFK015; 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one