BGC > Produktsuche > 2-Amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one | 10300-27-3
Lieferanten für CAS
10300-27-3
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Daten | CAS |
10300-27-3 | Formula |
C11H15N5O5 |
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8 Registerierte Lieferanten
Amadis Chemical Company Limited
P.R.China
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Leap Chem Co., Ltd
P.R.China
Molecular Formula: C11H15N5O5
Xinxiang Aurora Biotechnology Co., Ltd.
P.R.China
Finetech Industry Limited
P.R.China
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NewCan Biotech Limited
P.R.China
BOC Sciences
USA
Description: 3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. - Molecular Weight:297.27
- Boiling Point:711.7 °C at 760 mmHg
- Melting Point:263-300 °C
- Purity:≥95%
Molecular Formula: C11H15N5O5 Canonical SMILES: COC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)CO InChI: InChI=1S/C11H15N5O5/c1-20-7-4(2-17)21-10(6(7)18)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1 InChIKey: UYARPHAXAJAZLU-KQYNXXCUSA-N Solubility: In Vitro: DMSO : 25 mg/mL(84.10 mM;ultrasonic and warming and heat to 60°C) Appearance: White to Off-white Powder to Crystalline Powder Storage: Store at 2-8°C Synonyms: 3'-O-Methyl-D-guanosine; 3'-O-Methyl guanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one Weitere Informationen finden Sie hier
Chemlyte Solutions
P.R.China
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Santa Cruz Biotechnology, Inc.
USA
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