BGC > Produktsuche > (E)-N-[4-(1-Benzoyl-piperidin-4-yl)-butyl]-3-pyridin-3-yl-acrylamide | 658084-64-1

Molecular Formula: C24H29N3O2
Molecular Weight: 391.52
Hazard Symbols: Xn
WGKGermany: 3

Description:
FK866 is a non-competitive inhibitor of nicotinamide phosphoribosyltransferase (Nampt) with potential antineoplastic and antiangiogenic activities. FK866 binds to Nampt to suppress the biosynthesis of nicotinamide adenine dinucleotide (NAD+), leading to tumor cell apoptosis.

• Molecular Weight:391.515

Molecular Formula:
C24H29N3O2
Canonical SMILES:
C1CN(CCC1CCCCNC(=O)C=CC2=CN=CC=C2)C(=O)C3=CC=CC=C3
InChI:
InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+
InChIKey:
KPBNHDGDUADAGP-VAWYXSNFSA-N
Application:
potential anticancer agent
Synonyms:
Daporinad; (E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-pyridin-3-ylprop-2-enamide; APO 866; FK 866; APO866; FK866; APO-866; FK-866;