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Suppliers for
Panobinostat
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Properties | CAS |
404950-80-7 | Formula |
C21H23N3O2 |
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13 Registered suppliers
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Molecular Formula: C21H23N3O2 Molecular Weight: 349.42622 HS Code: 29339900
More details are to be found here
Molecular Formula: C21H23N3O2 Molecular Weight: 349.42622 HS Code: 29339900
More details are to be found here
Molecular Formula: C21H23N3O2 Molecular Weight: 349.42622 HS Code: 29339900
More details are to be found here
Description : Panobinostat is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis. In addition, this agent appears to modulate the expression of angiogenesis-related genes, such as hypoxia-inducible factor-1alpha (HIF-1a) and vascular endothelial growth factor (VEGF), thus impairing endothelial cell chemotaxis and invasion. HDAC is an enzyme that deacetylates chromatin histone proteins. - Molecular Weight :349.434
- Melting Point :114-117?C
- Purity :> 98%
Molecular Formula : C21H23N3O2 Canonical SMILES : CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO InChI : InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+ InChIKey : FPOHNWQLNRZRFC-ZHACJKMWSA-N Solubility : In vitro: 10 mM in DMSO Appearance : Light yellow to yellow Solid Application : Antineoplastic Agents Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month Synonyms : LBH589; LBH 589; LBH-589; NVP-LBH589; NVP-LBH 589; Panobinostat; trade name Farydak
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Purity : 98% Smile code : O=C(NO)/C=C/C1=CC=C(CNCCC2=C(C)NC3=C2C=CC=C3)C=C1 MDL Number : MFCD09833242 MolFormula : C21H23N3O2 MolWeight : 349.4300 Available in stock : 19.081
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Properties:
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Last update 2024-06-11
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