BGC > Product Search > Methyl 2,5-dihydroxycinnamate

Molecular Formula: C10H10O4
Molecular Weight: 194.18
Hazard Symbols: T
WGKGermany: 3

Assay: 99.0%min

Description :
Methyl 2,5-dihydroxycinnamate, a stable analog of erbstatin, is a stable, potent inhibitor of EGFR kinase activity. It is described to be four-times more stable than erbstatin in calf serum2. It was shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis.

• Molecular Weight :194.19
• Purity :≥98% by HPLC

Molecular Formula :
C10H10O4
Canonical SMILES :
COC(=O)C=CC1=C(C=CC(=C1)O)O
InChI :
InChI=1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3/b5-2+
InChIKey :
BQCNSTFWSKOWMA-GORDUTHDSA-N
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
Methyl 2,5-dihydoxycinnamate; 3-(2,5-dihydroxyphenyl)-2-propenoic acid, methyl ester; Erbstatin Analog

More details are to be found here

Description :
Methyl 2,5-dihydroxycinnamate, a stable analog of erbstatin, is a stable, potent inhibitor of EGFR kinase activity. It is described to be four-times more stable than erbstatin in calf serum2. It was shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis.

• Molecular Weight :194.19
• Purity :≥98% by HPLC

Molecular Formula :
C10H10O4
Canonical SMILES :
COC(=O)C=CC1=C(C=CC(=C1)O)O
InChI :
InChI=1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3/b5-2+
InChIKey :
BQCNSTFWSKOWMA-GORDUTHDSA-N
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
Methyl 2,5-dihydoxycinnamate; 3-(2,5-dihydroxyphenyl)-2-propenoic acid, methyl ester; Erbstatin Analog

More details are to be found here