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Appearance	Yellowish to white crystalline powder
Solubility	Soluble in water and sparingly soluble in methanol
Identification	NMR, HPLC,IR
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20ppm
Total impurity	≤ 1.5%
Single impurity	≤ 0.5%
Assay	≥ 98.5%

Molecular Formula: C29H31N7O
Molecular Weight: 493.6
HS Code: 29339900

Description:
Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome.

• Molecular Weight:493.60
• Boiling Point:451°C
• Melting Point:207-209°C
• Purity:>98%

Molecular Formula:
C29H31N7O
Canonical SMILES:
CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
InChI:
InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
InChIKey:
KTUFNOKKBVMGRW-UHFFFAOYSA-N
Solubility:
Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Appearance:
White to Off-white Solid
Storage: Store at -20°C
Synonyms:
CGP057148B; STI571; Gleevec; Glivec; N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide

Purity: 98%
Smile code: O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4
MDL Number: MFCD05662257
MolFormula: C29H31N7O
MolWeight: 493.6028
Available in stock: 881.011

Smile code:
O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4
MDL Number:
MFCD05662257
Purity :
98%
Available in stock:
616.01 g