BGC > Buscar Producto > 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one | 284028-89-3

Molecular Formula: C14H11F3N2OS
Molecular Weight: 312.3101496
Hazard Symbols: T
UN Number: UN 2811
WGKGermany: 3
PackingGroup: III
HS Code: 29349990

Molecular Formula: C14H11F3N2OS
Molecular Weight: 312.31

Description:
XAV 939 is a tankyrase (TNKS) inhibitor with IC50 values of 11 nM and 4 nM for tankyrase 1 and 2 respectively. XAV 939 antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. It also suppresses proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.

• Molecular Weight:312.31
• Melting Point:>230°C (dec.)
• Purity:0.98

Molecular Formula:
C14H11F3N2OS
Canonical SMILES:
C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
InChI:
InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
InChIKey:
KLGQSVMIPOVQAX-UHFFFAOYSA-N
Appearance:
White to Pale Yellow Solid
Application:
Differentiation
Synonyms:
XAV939; XAV 939; XAV-939. 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one