BGC > Buscar Producto > Incb39110 | 1334298-90-6

Molecular Formula: C26H23F4N9O
Molecular Weight: 553.53

Description:
Itacitinib is a potent and selective JAK1 inhibitor developed for the treatment of Graft-versus-host disease and non-small cell lung cancer.

• Molecular Weight:553.51
• Purity:>98%

Molecular Formula:
C26H23F4N9O
Canonical SMILES:
C1CN(CCC1N2CC(C2)(CC#N)N3C=C(C=N3)C4=C5C=CNC5=NC=N4)C(=O)C6=C(C(=NC=C6)C(F)(F)F)F
InChI:
InChI=1S/C26H23F4N9O/c27-20-18(1-7-32-22(20)26(28,29)30)24(40)37-9-3-17(4-10-37)38-13-25(14-38,5-6-31)39-12-16(11-36-39)21-19-2-8-33-23(19)35-15-34-21/h1-2,7-8,11-12,15,17H,3-5,9-10,13-14H2,(H,33,34,35)
InChIKey:
KTBSXLIQKWEBRB-UHFFFAOYSA-N
Solubility:
Soluble to > 35 mg/mL in DMSO.
Appearance:
Solid Powder
Storage: Store at -20 °C
Synonyms:
INCB 039110; 2-[1-[1-[3-fluoro-2-(trifluoromethyl)pyridine-4-carbonyl]piperidin-4-yl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile