Description:
SU4984 is a FLT3 inhibitor that induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3. It also exhibits inhibitory effects on C-KIT, VEGFR, and PDGFRβ.
Molecular Formula:
C15H13ClN2O
Canonical SMILES:
CC1=CC(=C(N1)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C
InChI:
InChI=1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-
InChIKey:
XLBQNZICMYZIQT-GHXNOFRVSA-N
Appearance:
Yellow Solid Powder
Synonyms:
SU5614; SU 5614; SU5614; (3Z)-5-chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one Weitere Informationen finden Sie
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