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Description	A white or almost white powder
Solubility	Freely soluble in methanol and in methylene chloride; very slightly soluble in acetonitrile; practically insoluble in water
Identification
A)	Ir Should Comply With The Reference Standard Spectrum
B)Hplc	The Spectrum Time Of The Major Peak In The Chromatogram Of The Sample Should Correspond That Of Standard
C)	The X-Ray Diffraction Pattern Conforms To That Of FormⅡ
Residue on ignition	Not more than 0.2%
Water (methodⅠ )	Nmt 0.5%
Heavy metals	Nmt 0.002%
Ethyl acetate	nmt 0.5%
N-heptane	nmt 0.5%
Tetrahydrofuran	nmt 0.072%
Related substance
Impurity e	nmt 0.3%
Impurity o	nmt 0.3%
Impurity t	nmt 0.2%
Any other impurity	nmt0.1%
Total imputity	nmt 1.0%
Asssay (on the anhydrous basis)	97.0% to 102

Molecular Formula: C37H48N6O5S2
Molecular Weight: 720.94

Description:
Ritonavir is an HIV protease inhibitor. It is often used in a low dose with another protease inhibitor lopinavir.

• Molecular Weight:720.95
• Boiling Point:947.0±65.0 °C at 760 mmHg
• Melting Point:120-122°C
• Purity:≥98%

Molecular Formula:
C37H48N6O5S2
Canonical SMILES:
CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
InChI:
InChI=1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
InChIKey:
NCDNCNXCDXHOMX-XGKFQTDJSA-N
Solubility:
In Vitro: DMSO: 25 mg/mL (34.68 mM; Need ultrasonic) H2O: < 0.1 mg/mL (insoluble) In Vivo: 1.Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: 2.5 mg/mL (3.47 mM); Clear solution; Need warming 2.Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline) Solubility: 2.5 mg/mL (3.47 mM); Suspended solution; Need ultrasonic
Appearance:
White Solid
Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms:
Norvir; ABT-538; A-84538; 538, ABT; ABT 538; ABT-538; ABT538; Abbott 84538

Purity: 98%
Smile code: O=C(N[C@@H](CC1=CC=CC=C1)[C@H](C[C@H](CC2=CC=CC=C2)NC([C@H](C(C)C)NC(N(CC3=CSC(C(C)C)=N3)C)=O)=O)O)OCC4=CN=CS4
MDL Number: MFCD00927142
MolFormula: C37H48N6O5S2
MolWeight: 720.9442
Available in stock: 2366.431

Smile code:
O=C(N[C@@H](CC1=CC=CC=C1)[C@H](C[C@H](CC2=CC=CC=C2)NC([C@H](C(C)C)NC(N(CC3=CSC(C(C)C)=N3)C)=O)=O)O)OCC4=CN=CS4
MDL Number:
MFCD00927142
Purity :
98%
Available in stock:
1729.73 g