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The indazole ring system is a known pharmacophore (bioactive structure) found in many drugs such as kinase inhibitors, anti-inflammatory agents, and anticancer compounds.
The bromo and iodo substituents make the molecule especially useful in cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald?Hartwig) to introduce other functional groups or aryl systems.
The 1-methyl substitution can influence lipophilicity and metabolic stability in lead compounds.
2. Agrochemical Research
Indazole derivatives have shown activity as plant growth regulators, fungicides, and herbicides.
Halogenated versions like this can serve as precursors to more complex agrochemicals through substitution or coupling chemistry.
3. Synthetic Building Block
The combination of bromine and iodine on the same aromatic ring offers orthogonal reactivity ? meaning chemists can selectively replace one halogen before the other, enabling stepwise synthesis of complex molecules.
Useful for preparing diversely substituted indazole derivatives for medicinal chemistry libraries or materials science.
4. Potential Use in Materials Science
Some halogenated heterocycles are studied for organic electronics (OLED emitters, semiconductors), although no specific data confirms this compound is currently used in that way ? it?s just structurally plausible.
Company Profile
Hanhong Group is a professional enterprise engaged in researching, developing, manufacturing and exporting unnatural amino acids, nucleosides, nucleotides, chiral chemicals and other fine chemicals in China, owning several branch companies. Shanghai Hanhong Chemical Co., LTD. is the core member of Hanhong Group. It is the window to the world of Hanhong Group products. It is business includes sales, R&D and manufacturing kilograms chemicals. It has owned a lot of senior researchers, including doctors, professors and experts of organic chemistry for R&D and process control. The company has built R&D center in the Universities, and has established pilot plant owning over 50 sets of various reactors from 10L-5000L. Binhai Hanhong Biochemical Co., LTD. is the total venture company of Shanghai Hanhong Chemical Co., Ltd., mainly produces pesticides, dyestuffs, pharmaceutical materials and their intermediates. It is located in Yancheng Coastal Chemical Zone, which is the famous chemical zone in China. It covers an area of 35,000m2 including four multifunction chemical plants, one pilot plant, one waste water treating plant and labs. The company has 80 employees. There are over 40 sets of reactors from 50L-8000L.It possesses such advanced analytic instruments as HPLC, GC, HPCE and etc. Other members of Hanhong Group are Shanxi Hanhong Chemical Co., LTD., mainly producing biochemicals, Shijiazhuang Hanhong Biochemical Co., LTD., mainly producing chiral chemicals and Shandong Hanhong Biochemical Co.,LTD., mainly producing nucleosides and nucleotides. Relying on its R&D and producing facilities, Hanhong Groupcan manufacture custom-made products from grams to tons.
