CAS No. 941678-49-5

Molecular Formula: C17H18N6
Molecular Weight: 306.371
HS Code: 29335990

EINECS:1312995-182-4
Molecular formula:C17H18N6

Molecular Weight: 306.37
Molecular Formula: C17H18N6
Canonical SMILES: C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChI: InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
InChIKey: HFNKQEVNSGCOJV-OAHLLOKOSA-N
Melting Point: 84-89°C
Purity: >98%
Solubility: Soluble in aqueous buffers across a pH of 1-8
Synonyms: (R)-Ruxolitinib; INCB018424; R-INCB018424; (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Description
Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM respectively in cell-free assays, and has > 130-fold selectivity for JAK1/2 versus JAK3.


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Smile code:
N#CC[C@]([H])(C1CCCC1)N2C=C(C=N2)C3=C4C=CN=C4NC=N3
MDL Number:
MFCD12031592
Purity :
98%
Available in stock:
16.046 g