Description:
S107 is a type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. S107 increased FKBP12 binding to RyR1 in SR vesicles in the presence of reduced glutathione and the NO-donor NOC12, with no effect in the presence of oxidized glutathione.
- Molecular Weight: 209.31
- Molecular Formula: C11H15NOS
Canonical SMILES:
CN1CCSC2=CC=C(OC)C=C2C1.[H]Cl
InChI:
1S/C11H15NOS.ClH/c1-12-5-6-14-11-4-3-10(13-2)7-9(11)8-12;/h3-4,7H,5-6,8H2,1-2H3;1H
InChIKey: PKLKSAHANRLKJK-UHFFFAOYSA-N- Boiling Point: 318.8±42.0 °C at 760 Torr
- Appearance: Solid powder
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
2,3,4,5-Tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine hydrochloride; S107; S-107; S 107.
More details are to be found on supplier website
