Molecular Weight: 312.40
Molecular Formula: C20H24O3
Canonical SMILES: CC(C)C1=C(C2=C(C=C1)[C@]3(CCC4=C([C@@H]3CC2)COC4=O)C)O
InChI: InChI=1S/C20H24O3/c1-11(2)12-4-6-16-14(18(12)21)5-7-17-15-10-23-19(22)13(15)8-9-20(16,17)3/h4,6,11,17,21H,5,7-10H2,1-3H3/t17-,20+/m0/s1
InChIKey: KPXIBWGPZSPABK-FXAWDEMLSA-N
Boiling Point: 490.0±45.0 °C | Condition: Press: 760 Torr
Melting Point: 232-233 °C
Purity: >98%
Solubility: Soluble in DMSO
Application: triptophenolide can remarkably inhibit the delayed type hypersensitivity (DTH) reaction induced by DNCB and BSA in vitro. It also could diminishe the peripheral blood ANAE+lymphocytes in rats and micc. It can significautly increase the amount of total serum complement and dramatically decrcase the serum antibody products (1gG ) of rats and mice.
Storage: Store at -20 °C
Synonyms: Tryptophenolide; Hypolide; Phenanthro(1,2-c)furan-1(3H)-one, 3b,4,5,9b,10,11-hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)-, (3bR-trans)-; (+)-Triptophenolide; (3bR,9bS)-6-Hydroxy-7-isopropyl-9b-methyl-3b,4,5,9b,10,11-hexahydrophenanthro[1,2-c]furan-1(3H)-one; (3bR,9bS)-3b,4,5,9b,10,11-Hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)phenanthro[1,2-c]furan-1(3H)-one
DescriptionTriptophenolide is a natural product derived from the traditional Chinese medicinal plant Tripterygium wilfordii. It is a diterpenoid compound known for its diverse biological activities, including anti-inflammatory, immunosuppressive, and anticancer properties.
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