Description:
Delamanid is used for the treatment of multi-drug-resistant tuberculosis. It functions by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall.
- Molecular Weight: 534.492
- Molecular Formula: C25H25F3N4O6
Purity: ≥98%
Canonical SMILES:
CC1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
InChI:
InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1
InChIKey: XDAOLTSRNUSPPH-XMMPIXPASA-N
- Melting Point: >189°C (dec.)
- Solubility: Soluble in DMSO, not in water
- Appearance: White to Off-white to Pale Yellow Powder
- Application: the treatment of multi-drug-resistant tuberculosis
- Storage: Store at -20 °C
Synonyms:
OPC-67683; OPC 67683; OPC67683; Deltyba; (2R)-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenoxy]methyl]-3H-imidazo[2,1-b][1,3]oxazole
More details are to be found on supplier website
