Description:
Ansamitocin P 3' is an isomer of Ansamitocin P-3, a potent anti-tumor maytansinoid antibiotic found in Actinosynnema pretiosum, a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29.
- Molecular Weight: 635.14
- Molecular Formula: C32H43ClN2O9
Purity: >98%
Canonical SMILES:
CCCC(=O)OC1CC(=O)N(C2=C(C(=CC(=C2)CC(=CC=CC(C3(CC(C(C4C1(O4)C)C)OC(=O)N3)O)OC)C)OC)Cl)C
InChI:
InChI=1S/C32H43ClN2O9/c1-8-10-27(37)43-25-16-26(36)35(5)21-14-20(15-22(40-6)28(21)33)13-18(2)11-9-12-24(41-7)32(39)17-23(42-30(38)34-32)19(3)29-31(25,4)44-29/h9,11-12,14-15,19,23-25,29,39H,8,10,13,16-17H2,1-7H3,(H,34,38)/b12-9+,18-11+/t19-,23+,24-,25+,29+,31+,32+/m1/s1
InChIKey: WLKHTIAFMSHJLG-BYXOJEECSA-N
- Boiling Point: 837.6±65.0°C (Predicted)
- Melting Point: 182-185°C
- Solubility: Soluble in ethanol (1 mg/ml), methanol (10 mg/ml), DMF (20 mg/ml)
- Appearance: White to Off-white Crystalline Solid
- Application: ADCs Cytotoxin
- Storage: Store at 2-8°C
Synonyms:
Ansamitocin P3'; AP-3'; Ansamitocin P-3'; Maytansinol butyrate, Maytansinoid AP-3'. Antibiotic C 15003P3'; iso-Ansamitocin P-3
More details are to be found on supplier website
