Description:
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects. Sophocarpine significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway.
- Molecular Weight: 246.35
- Molecular Formula: C15H22N2O
Purity: >98%
Canonical SMILES:
C1CC2CN3C(CC=CC3=O)C4C2N(C1)CCC4
InChI:
InChI=1S/C15H22N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h1,7,11-13,15H,2-6,8-10H2/t11-,12+,13+,15-/m0/s1
InChIKey: AAGFPTSOPGCENQ-JLNYLFASSA-N
- Boiling Point: 425.4±45.0 °C at 760 mmHg
- Melting Point: 54~55°C
- Solubility: In vitro: 10 mM in DMSO
- Appearance: Powder
- Application: anti-tumor; anti-cancer; antiarrhythmic;
- Storage: Powder: -20°C: 3 years4°C: 2 yearsIn solvent: -80°C: 6 months-20°C: 1 month
Synonyms:
AS 604850; AS604850; AS-604850; 13,14-Didehydromatridin-15-one; (7aS,13aR,13bR,13cS)-2,3,6,7,7a,8,13,13a,13b,13c-decahydro-1H,5H,10H-dipyrido[2,1-f: 3',2',1'-ij][1,6]naphthyridin-10-one
More details are to be found on supplier website
