CAS No. 60-82-2

Molecular Formula: C15H14O5

Molecular Formula: C15H14O5
Molecular Weight: 274.27
Hazard Symbols: Xi
WGKGermany: 3
HS Code: 29145090

More details are to be found on supplier website

Cosmate®PHR,Phloretin is a plant polyphenol with a dihydrochalcone structure. It is present in the peel and root bark of succulent fruits such as apples and pears, and in various vegetable juices. Phloretin has abundant biological activities, such as anti-oxidation, anti-tumor, blood sugar lowering, blood vessel protection, etc. And Phloretin can inhibit tyrosinase activity, enhance skin permeability. It also helps other whitening ingredients to enter the skin to exert their biological activity. At the same time, Phloretin can scavenge free radicals, reduce the keratinocytes damage caused by ultraviolet rays; and it also has antibacterial activity. It has many beauty effects including anti-aging, whitening skin, anti-inflammation, and removing acne. Phloretin can dilute pigmentation and whiten skin. Its effect is better than other common whitening agents such as kojic acid and arbutin. It is a new favorite whitening agent in cosmetics market.
Appearance	White to off-white powder
Odor	None to slight
Particle Size	95% Through 80 mesh
Solubility	Clear
Heavy metals	10 ppm max.
As	1 ppm max.
Hg	0.1 ppm max.
Pb	1 ppm max.
Cd	1 ppm max.
Water	5.0% max.
Ash	0.1%max.
Methanol	100 ppm max.
Ethanol	1,000 ppm max.
Assay	98.0% min.
Total number of Bacteria	1,000cfu/g max.
Yeasts & Molds	100 cfu/g max.
Salmonella	Negative
Escherichia Coli	Negative
Applications	Whitening Agent,Antioxidant,Skin-Soothing,Anti-inflammatory,Antiseborrhoeic,Sun Screen

Phloretin is a dihydrochalcone,a type of natural phenol. Phloretin is a member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2′, 4′ and 6′. It has a role as a plant metabolite and an antineoplastic agent. It derives from a dihydrochalcone.

Phloretin is a plant polyphenol with a dihydrochalcone structure. It is present in the peel and root bark of succulent fruits such as apples and pears, and in various vegetable juices. Phloretin has abundant biological activities, such as anti-oxidation, anti-tumor, blood sugar lowering, blood vessel protection, etc. And Phloretin can inhibit tyrosinase activity, enhance skin permeability. It also helps other whitening ingredients to enter the skin to exert their biological activity. At the same time, Phloretin can scavenge free radicals, reduce the keratinocytes damage caused by ultraviolet rays; and it also has antibacterial activity. It has many beauty effects including anti-aging, whitening skin, anti-inflammation, and removing acne. Phloretin can dilute pigmentation and whiten skin. Its effect is better than other common whitening agents such as kojic acid and arbutin. It is a new favorite whitening agent in cosmetics market.

Description:
Phloretin, a type of natural phenol found in the peels of apples, is a dihydrochalcone that shows beneficial effects on diabetes. Phloretin has whitening, freckle removal, anti-aging, strong antioxidant, and photoprotective effects. It can also inhibit the activity of matrix metalloproteinase (MMP-1) and elastase, which can degrade skin connective tissue and play an important role in the process of skin photoaging. Phloretin has excellent immunosuppressive and anti-inflammatory effects. Phloretin can significantly inhibit the levels of nitrogen oxide, prostaglandin E2, IL-6, TNF-α, iNOS and COX-2, inhibit the nuclear translocation of NF-JB subunit p65 protein, and reduce phosphorylation in the MAPK pathway. It can be used in facial masks, skin creams, lotions and essences.

• Molecular Weight: 274.27
• Molecular Formula: C15H14O5

Purity: >98%

Canonical SMILES:
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O

InChI:
InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2

InChIKey: VGEREEWJJVICBM-UHFFFAOYSA-N

• Boiling Point: 534.4±29.0°C at 760 Torr
• Melting Point: 263.5°C (dec.)
• Solubility: Soluble in Acetonitrile (Slightly), Methanol (Slightly)
• Appearance: White to off-white powder
• Application: antimicrobial activity
• Storage: Store at 2-8°C

Synonyms:
Dihydronaringenin; NSC 407292; NSC-407292; NSC407292; RJC 02792; RJC02792; RJC-02792; 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone; Propiophenone, 2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-; 2',4',6'-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone; 2',4',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone; Dihydronaringenin; Naringenin dihydrochalcone; NSC 407292; Phloretol; RJC 02792; α,β-Dihydrochalconaringenin; β-(p-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone; β-(p-Hydroxyphenyl)phloropropiophenone

More details are to be found on supplier website

Smile code:
O=C(C1=C(O)C=C(O)C=C1O)CCC2=CC=C(O)C=C2
MDL Number:
MFCD00002288
Purity :
98%
Available in stock:
433.907 g