CAS No. 58749-23-8

Molecular Formula: C16H14O5

Molecular Weight: 286.28
Molecular Formula: C16H14O5
Canonical SMILES: COC1=C(C=CC(=C1O)O)/C=C/C(=O)C2=CC=C(C=C2)O
InChI: InChI=1S/C16H14O5/c1-21-16-11(5-9-14(19)15(16)20)4-8-13(18)10-2-6-12(17)7-3-10/h2-9,17,19-20H,1H3/b8-4+
InChIKey: DRDRYGIIYOPBBZ-XBXARRHUSA-N
Boiling Point: 550.5±50.0 °C at 760 mmHg
Melting Point: 196-197 °C
Purity: >98%
Solubility: Soluble in Acetone, Chloroform, Dichloromethane, DMSO, Ethyl Acetate, Water (Slightly)
Storage: Store at -20 °C
Synonyms: (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (E)-; (E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 3,4,4'-Trihydroxy-2-methoxy-trans-chalcone; 3,4,4'-Trihydroxy-2-Methoxychalcone
Description
Licochalcone B is extracted from the roots of Glycyrrhiza glabra L. It inhibits the adhesion,invasion and metastasis of human malignant bladder cancer T24 cells. It could significantly reduce the LPS-induced production of NO, TNFalpha and MCP-1.


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