Description:
Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties. Aloperine induces apoptosis and autophagy in HL-60 cells.
- Molecular Weight: 232.36
- Molecular Formula: C15H24N2
Purity: >98%
Canonical SMILES:
C1CCN2CC3CC(C2C1)C=C4C3NCCC4
InChI:
InChI=1S/C15H24N2/c1-2-7-17-10-13-9-12(14(17)5-1)8-11-4-3-6-16-15(11)13/h8,12-16H,1-7,9-10H2/t12-,13+,14+,15+/m0/s1
InChIKey: SKOLRLSBMUGVOY-GBJTYRQASA-N
- Boiling Point: 367.7±37.0 °C at 760 mmHg
- Melting Point: 69 - 71°C
- Solubility: In Vitro: DMSO : ≥ 100 mg/mL(82.19 mM)to 60°C)H2O : < 0.1 mg/mLIn Vivo: 1.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% salineSolubility: ≥ 2.08 mg/mL (8.95 mM); Clear solution2.Add each solvent one by one: 10% DMSO >> 90% (20%SBE-β-CDin saline)Solubility: ≥2.08 mg/mL (8.95 mM); Clear solution3.Add each solvent one by one: 10% DMSO >> 90%corn oilSolubility: ≥ 2.08 mg/mL (8.95 mM); Clear solution
- Appearance: White to off-white (Solid)
- Application: Anti-inflammatory, antibacterial, antiviral, and antitumor
- Storage: Powder: -20°C 3 yearsIn solvent: -80°C 6 months
Synonyms:
(6R,6aR,13S,13aS)-1,3,4,6,6a,7,8,9,10,12,13,13a-Dodecahydro-2H-6,13-methanodipyrido[1,2-a: 3',2'-e]azocine; (7-alpha,9-alpha)-9-De-2-piperidinyl-16,17-didehydro-ormosanine; Ormosanine, 16,17-didehydro-9-de-2-piperidinyl-, (7-alpha,9-alpha)-; Allopterin; 6,13-Methano-2H-dipyrido[1,2-a: 3',2'-e]azocine,1,3,4,6,6a,7,8,9,10,12,13,13a-dodecahydro-,[6R-(6α,6aβ,13α,13aα)]-
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