Description:
3-Methyladenine is an autophagy inhibitor that protects cerebellar granule cells (CGCs) from apoptosis following serum/potassium deprivation. 3-Methyladenine inhibits phosphoinositide 3-kinase (PI3K) activity, which plays a key role in autophagy process.
- Molecular Weight: 149.15
- Molecular Formula: C6H7N5
Purity: ≥98% by HPLC
Canonical SMILES:
CN1C=NC(=C2C1=NC=N2)N
InChI:
InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
InChIKey: FSASIHFSFGAIJM-UHFFFAOYSA-N
- Boiling Point: 240.1±50.0°C at 760 mmHg
- Melting Point: >260°C (dec.)
- Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)
- Appearance: White Solid
- Storage: Store at 2-8°C
Synonyms:
NSC 66389; NSC-66389; NSC66389; 6-Amino-3-methylpurine; 3-MA; 3H-Purin-6-amine, 3-methyl-; 3-Methyl Adenine; 3-Methyl-6-aminopurine; N3-Methyladenine
More details are to be found on supplier website
