Description:
Acetyl Hexapeptide-1, also known as Melitane, is a biomimetic peptide antagonist of the α-MSH (α-Melanocyte-Stimulating Hormone). It stimulates tyrosinase activity, melanin synthesis and melanocyte dendricity, and protects DNA damage caused by UV exposure.
- Molecular Weight: 870.01
- Molecular Formula: C43H59N13O7
Purity: 98%
Canonical SMILES:
CCCCC(C(=O)NC(C)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)N)NC(=O)C
InChI:
InChI=1S/C43H59N13O7/c1-4-5-15-32(52-26(3)57)39(60)51-25(2)38(59)55-36(21-29-23-47-24-50-29)42(63)56-35(19-27-12-7-6-8-13-27)41(62)53-33(17-11-18-48-43(45)46)40(61)54-34(37(44)58)20-28-22-49-31-16-10-9-14-30(28)31/h6-10,12-14,16,22-25,32-36,49H,4-5,11,15,17-21H2,1-3H3,(H2,44,58)(H,47,50)(H,51,60)(H,52,57)(H,53,62)(H,54,61)(H,55,59)(H,56,63)(H4,45,46,48)/t25-,32-,33-,34-,35+,36-/m0/s1
InChIKey: WPIQUSRULDNCKM-IFSWANACSA-N
Synonyms:
L-Tryptophanamide, N-acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-; N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide; Acetyl hexapeptide 1; Melitane; Melitane GL; Melitane GL 200; Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2
More details are to be found on supplier website
