Molecular Weight: 436.41
Molecular Formula: C21H24O10
Canonical SMILES: C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)OC3C(C(C(C(O3)CO)O)O)O)O)O
InChI: InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-12-7-14(25)17(15(26)8-12)13(24)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-23,25-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1
InChIKey: GSTCPEBQYSOEHV-QNDFHXLGSA-N
Boiling Point: 787.9±60.0 °C at 760 mmHg
Melting Point: 163 °C
Purity: >98%
Solubility: Soluble in DMF, DMSO, Ethanol
Application: Anti-inflammatory
Storage: Store at 2-8 °C, protect from light
Synonyms: 1-[4-(β-D-Glucopyranosyloxy)-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; p-Phloridzin; Phloretin 4'-glucoside; Phloretin 4'-β-D-glucoside; Phloretin-4-O-glycoside; Phloretin-4'-O-β-D-glucopyranoside; Phloretine-4'-glucoside; Prunin dihydrochalcone; Trilobatin
DescriptionTrilobatin, coming from the herbs of Lithocarpus pachyphyllus, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway. It increased superoxide dismutase (SOD) activity. Besides, Trilobatin is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect.
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