Description:
L-Theanine is a glutamine analog found in the green tea plant. It can bind to glutamate receptors and inhibit glutamate transporters, which exhibits a neuroprotective effect. It promotes self-renewal of human embryonic stem cells (hESCs).
- Molecular Weight: 174.20
- Molecular Formula: C7H14N2O3
Purity: Assay: 98%-102%
Canonical SMILES:
CCNC(=O)CCC(C(=O)O)N
InChI:
InChI=1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
InChIKey: DATAGRPVKZEWHA-YFKPBYRVSA-N
- Boiling Point: 430.2±40.0 °C (Predicted)
- Melting Point: 202-215 °C
- Appearance: White Solid Powder
- Application: L-theanine, an amino acid found primarily in tea leaves, has been widely recognized for its potential applications in drug discovery and development. This natural compound has been widely studied for its various health benefits, including its ability to promote relaxation, reduce stress, and improve cognitive function. In recent years, scientists have begun to explore L-theanine's potential in drug discovery due to its unique pharmacological properties and therapeutic potential.L-theanine is known to cross the blood-brain barrier, allowing it to have an effect on the central nervous system. This ability makes it a promising candidate for the development of drugs for neurological disorders such as anxiety, depression, and cognitive impairment. Studies have shown that L-theanine can modulate neurotransmitter levels in the brain, including increasing levels of gamma-aminobutyric acid (GABA), dopamine, and serotonin, which play a crucial role in regulating mood, stress responses, and cognitive function.One area where L-theanine has shown promise in drug discovery is in the treatment of anxiety disorders. Preclinical studies have shown that L-theanine can reduce anxiety-like behaviors in animal models by increasing GABA levels and modulating neurotransmitter activity in the brain. These findings suggest that L-theanine could be developed into an antianxiety medication with fewer side effects than traditional antianxiety drugs.In addition, L-theanine's neuroprotective effects have sparked interest in its potential use in preventing and treating neurodegenerative diseases such as Alzheimer's and Parkinson's. Studies have shown that L-theanine's antioxidant and anti-inflammatory properties may help protect neurons from damage and support brain health. By targeting multiple pathways involved in neurodegeneration, L-theanine could offer a new treatment approach for these devastating diseases.Another area of drug discovery where L-theanine shows promise is in improving the efficacy and reducing the side effects of existing drugs. For example, combining L-theanine with stimulant drugs used to treat attention deficit hyperactivity disorder (ADHD) has been shown to improve cognition and reduce the risk of side effects such as anxiety and insomnia. This synergistic effect could lead to the development of more effective and well-tolerated treatments for ADHD and other conditions.In addition to its potential applications in neurological and psychiatric diseases, L-theanine has also shown promise in oncology and immunology research. Multiple studies have shown that L-theanine can enhance the anti-tumor activity of chemotherapy drugs and improve immune function, indicating its potential use as an adjuvant therapy for cancer patients. By modulating immune responses and reducing inflammation, L-theanine can help increase the efficacy of cancer treatments and improve patient outcomes.In addition, L-theanine's anti-inflammatory properties make it a promising candidate for the development of drugs for chronic inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. By inhibiting pro-inflammatory cytokines and promoting the production of anti-inflammatory molecules, L-theanine can help slow disease progression and relieve symptoms in patients with these diseases.
- Storage: Store at 2-8 °C
Synonyms:
N-Ethyl-L-glutamine; Theanin; Suntheanine; (S)-2-Amino-5-(ethylamino)-5-oxopentanoic acid; N5-Ethyl-L-glutamine
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