Molecular Weight: 262.35
Molecular Formula: C15H22N2O2
Canonical SMILES: C1CC2CN3C(CC=CC3=O)C4C2[N+](C1)(CCC4)[O-]
InChI: InChI=1S/C15H22N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h1,7,11-13,15H,2-6,8-10H2/t11-,12+,13+,15-,17+/m0/s1
InChIKey: QMGGMESMCJCABO-JARXUMMXSA-N
Purity: ≥90% by HPLC
Solubility: Soluble in DMSO
Application: human HERG inhibitor
Storage: Store at 2-8°C
Synonyms: 1-oxy-13,14-didehydro-matridin-15-one; N-oxosophocarpine; Sophocarpidine
DescriptionSophocarpidine comes from the root of Styphnolobium japonicum (L.) Schott. Sophocarpine could decrease the level of serum transaminase, improve lipid metabolism, reduce synthesis of inflammatory cytokines TNF-α, TGF-β1 and IL-6, activate protective adipocytokine adiponectin, might be a drug for colonic inflammation and NASH.
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