Molecular Weight: 410.92
Molecular Formula: C22H28ClFO4
Canonical SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C
InChI: InChI=1S/C22H28ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChIKey: FCSHDIVRCWTZOX-DVTGEIKXSA-N
Boiling Point: 555.1±50.0 °C at 760 mmHg
Melting Point: 216-222 °C (dec.)
Purity: >95%
Solubility: Soluble in Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
Application: Anti-inflammatory agents; glucocorticoids
Storage: Store at -20 °C
Synonyms: Clobetasol Propionate EP Impurity G; (11β,16β)-21-Chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione; Clobetasol Propionate Impurity G; Dovate; Clobecort Amex; (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
DescriptionClobetasol is a highly potent topical corticosteroid used to treat various skin conditions such as eczema and psoriasis. It works by reducing inflammation, redness, itching, and rashes. Clobetasol has strong anti-inflammatory, antipruritic, and vasoconstrictive properties.
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