Description:
An antiretroviral medication acts as a protease inhibitor. It is a co-formulation with a sub-therapeutic dose of ritonavir, as a component of combination therapy to treat HIV/AIDS.
- Molecular Weight: 628.81
- Molecular Formula: C37H48N4O5
Purity: ≥98%
Canonical SMILES:
CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O
InChI:
InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
InChIKey: KJHKTHWMRKYKJE-SUGCFTRWSA-N
- Boiling Point: 924.2±65.0 °C at 760 mmHg
- Melting Point: 95-98°C
- Solubility: In Vitro: DMSO: 100 mg/mL (159.03 mM; Need ultrasonic)In Vivo: 1.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% salineSolubility: ≥ 2.5 mg/mL (3.98 mM); Clear solution2.Add each solvent one by one: 10% DMSO >> 90% corn oilSolubility: ≥ 2.5 mg/mL (3.98 mM); Clear solution
- Appearance: White Solid
- Storage: Store at -20°C
Synonyms:
ABT 378; ABT-378; ABT378; Aluviran; Kaletra
More details are to be found on supplier website
