Description:
Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM.
- Molecular Weight: 264.3
- Molecular Formula: C14H20N2O3
Purity: >98%
Canonical SMILES:
C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
InChI:
InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
InChIKey: WAEXFXRVDQXREF-UHFFFAOYSA-N
- Melting Point: 161-164 °C
- Solubility: In Vitro: 10 mM in DMSO
- Appearance: White Solid
- Application: Antineoplastic agents; histone deacetylase inhibitors
- Storage: Powder: -20°C: 3 years4°C: 2 yearsIn solvent: -80°C: 6 months-20°C: 1 month
Synonyms:
MK-0683, MK 0683, MK0683, SAHA, M344, CCRIS 8456, HSDB 7930, Vorinostat, suberoylanilide hydroxamic acid, Zolinza
More details are to be found on supplier website
