Molecular Weight: 264.3
Molecular Formula: C14H20N2O3
Canonical SMILES: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
InChI: InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
InChIKey: WAEXFXRVDQXREF-UHFFFAOYSA-N
Melting Point: 161-164 °C
Purity: >98%
Solubility: In Vitro:
10 mM in DMSO
Application: Antineoplastic agents; histone deacetylase inhibitors
Storage: Powder:
-20°C: 3 years
4°C: 2 years
In solvent:
-80°C: 6 months
-20°C: 1 month
Synonyms: MK-0683, MK 0683, MK0683, SAHA, M344, CCRIS 8456, HSDB 7930, Vorinostat, suberoylanilide hydroxamic acid, Zolinza
DescriptionVorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM.
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